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The principal cytochrome P450 isoenzyme concerned appears to become CYP2E1, with CYP1A2 and CYP3A4 as added pathways. Around eighty five% of the oral dose seems within the urine inside 24 hours of administration, most given that the glucuronide conjugate, with small quantities of other conjugates and unchanged drug [see OVERDOSAGE] for toxicity inf
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